Molecular Characterization of SehB, a Type II Antitoxin of Salmonella enterica Serotype Typhimurium: Amino Acid Residues Involved in DNA-Binding, Homodimerization, Toxin Interaction, and Virulence

Molecular pathogenesis of Salmonella enterica serotype typhimurium-induced diarrhea.

Molecular Pathogenesis of Salmonella enterica Serotype Typhimurium-Induced Diarrhea Shuping Zhang, Robert A. Kingsley, Renato L. Santos, Helene Andrews-Polymenis, Manuela Raffatellu, Josely Figueiredo, Jairo Nunes, Renee M. Tsolis, L. Garry Adams, and Andreas J. Bäumler* Department of Veterinary Pathobiology, College of Veterinary Medicine, Texas A&M University, and Department of Medical Microb...

Molecular Characterization of a Salmonella Typhimurium Isolate from Caspian Pony

Typhoid disease or salmonellosis is a common sickness in horses. In several epidemiological studies inhospitalized horses, several serotypes of Salmonella often are predominant in nosocomial infections.Transportation, overcrowding, dehydration, oral antimicrobial therapy and infections are the risk factorswhich may activate latent or subclinical salmonellosis. In this study, t...

Serovar Typhimurium Salmonella enterica Virulence Regulatory Proteins of DNA-Binding Activities of the HilC and HilD

Ciprofloxacin-Resistant Salmonella enterica Serotype Typhimurium, China

We characterized 44 Salmonella enterica serotype Typhimurium isolates from Tongji Hospital outpatients in Wuhan, China, May 2002-October 2005. All 31 ciprofloxacin-resistant isolates were also resistant to > or = 8 other antimicrobial drugs and carried > or = 2 mutations in GyrA and 1 mutation in ParC. Class 1 integrons were identified in 37 isolates.

A Toxin-Antitoxin Module of Salmonella Promotes Virulence in Mice

Toxin-antitoxin (TA) modules are widely prevalent in both bacteria and archaea. Originally described as stabilizing elements of plasmids, TA modules are also widespread on bacterial chromosomes. These modules promote bacterial persistence in response to specific environmental stresses. So far, the possibility that TA modules could be involved in bacterial virulence has been largely neglected, b...